Lysistrata
The women of Athens withhold sex until their husbands stop the Peloponnesian War. Aristophanes wrote it as a bawdy comedy during an actual war, and the joke is that it almost sounds reasonable. Twenty-four hundred years later, anti-war protesters still invoke Lysistrata, which says something about both the play and the species.
Modern productions sell it as feminist; Aristophanes wrote a dirty joke performed entirely by men, complete with the running gag that the women can barely keep the strike themselves. Topical Athens jokes die without footnotes, the second half is mostly men staggering around in stage erections, and your experience depends heavily on which translator handled the obscenity.
The case for it and the rest of the canon open with Pro.
